您現在的位置:首頁 > 通知信息 > 學術通知
【“天工论坛”第25期】Innovation by Evolution: Bringing New Chemistry to Life
  星空娱乐平台:2019-10-17    供稿部門:
Prof. Frances Arnold
美國加州理工學院教授
2018年諾貝爾化學獎獲得者
美國國家科學院、美國國家工程院、美國國家醫學院院士
中國科學院天津工业生物技术研究所/合成生物技术创新中心国际咨询指导专家委员会成员
 
   報告題目:Innovation by Evolution: Bringing New Chemistry to Life
   報告時間:10月19日(周六) 17:30
   報告地點:天津工業生物所 B301階梯教室
   報告摘要:Not satisfied with nature’s vast catalyst repertoire, we want to create new protein catalysts and expand the space of genetically encoded enzyme functions. I will describe how we can use the most powerful biological design process, evolution, to optimize existing enzymes and invent new ones, thereby circumventing our profound ignorance of how sequence encodes function. Using mechanistic understanding and mimicking nature’s evolutionary processes, we can generate whole new enzyme families that catalyze synthetically important reactions not known in biology. Recent successes include selective carbene insertion to form C-Si and C-B bonds, and alkyne cyclopropanation to make highly strained carbocycles, all in living cells. Extending the capabilities and uncovering the mechanisms of these new enzymes derived from natural iron-heme proteins provides a basis for discovering new biocatalysts for increasingly challenging reactions. These new capabilities increase the scope of molecules and materials we can build using synthetic biology and move us closer to a sustainable world where chemical synthesis can be fully programmed in DNA.
   報告人簡介:
   Frances Arnold is the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry at the California Institute of Technology, where she has been on the faculty since 1986. She is the first American woman to win the Nobel Prize in Chemistry (2018). Arnold pioneered directed protein evolution and has used those methods for applications in alternative energy, chemicals, and medicine. Arnold received the Charles Stark Draper Prize of the US National Academy of Engineering in 2011, the US National Medal of Technology and Innovation from President Obama in 2013, and the Millennium Technology Prize in 2016; she has been elected to all three US National Academies of Science, Medicine, and Engineering. 
   Co-inventor on 58 issued US patents and active in technology transfer, Arnold co-founded Gevo, Inc. in 2005 to make fuels and chemicals from renewable resources, Provivi, Inc. in 2014 to develop non-toxic modes of agricultural pest control, and Aralez, Inc. in 2019 to develop sustainable biocatalytic processes for producing medicines and chemicals. Arnold received her B.S. in Mechanical and Aerospace Engineering from Princeton University and worked at the Solar Energy Research Institute, a national laboratory devoted to alternative energy research (now NREL) before obtaining her Ph.D. in Chemical Engineering from the University of California, Berkeley. Arnold chairs the Advisory Panel of the David and Lucile Packard Foundation Fellowships in Science and Engineering and is a Trustee of the Gordon Research Conferences.
 
   第25期天工论坛海报:
打印】  【關閉】  【返回
Copyright 2012 All Rights Reserved 中國科學院天津工业生物技术研究所 版权所有
通訊地址:天津空港經濟區西七道32號,郵編:300308
网址:http://www.dianzijidian.com
京ICP備05002857號网站地图
热门关键词:

星空娱乐游戏| 星空娱乐老虎机| 星空娱乐娱乐登陆| 星空娱乐官网网站| 星空娱乐官方网址| 星空娱乐网址多少| 星空娱乐官方下载| 星空娱乐官方网站| 星空娱乐平台注册| 星空娱乐网址| 星空娱乐娱乐城| 星空娱乐app注册| 星空娱乐首页| 星空娱乐官网下载| 星空娱乐平台| 星空娱乐下载app| 星空娱乐网站| 星空娱乐网页版| 星空娱乐注册| 星空娱乐开户| 星空娱乐网投| 星空娱乐登录| 星空娱乐平台登陆| 星空娱乐娱乐场| 星空娱乐平台官网| 星空娱乐电子游戏| 星空娱乐客户端| 星空娱乐官网| 星空娱乐在线|